Great yellow gentian
Secoiridoids (amarogentin, sweroside): these substances are responsible for the bitterness. They stimulate the production of gastric juices via the vagus nerve and, consequently, have a stimulant effect on the digestion. They protect the liver against the aggression of toxins.
Alkaloids (gentiannine, gentianidine): a bitter flavour, anti-inflammatory and calming action.
Flavonoids (isovitexin): antioxidant and calming action.
- Community herbal monograph on Gentiana lutea l., Radix
Committee On Herbal Medicinal Products (Hmpc)
Doc. Ref.: EMA/HMPC/578324/2008
- Smooth muscle relaxing activity of gentiopicroside isolated from Gentiana spathacea.
Rojas A, Bah M, Rojas JI, Gutiérrez DM.
Planta Med. 2000 Dec;66(8):765-7.
- Phytochemicals of Gentianaceae: A Review of Pharmacological Properties
Herbal division, Ind-Swift Ltd, Chandigar, India.
Pharma Book Syndicate: http://www.pharmabooksyndicate.com/issues/33.pdf
- Bitterness values for traditional tonic plants of southern Africa.
Olivier DK, van Wyk BE.
J Ethnopharmacol. 2013 Jun 3;147(3):676-9.
- Antimicrobial activity of Gentiana lutea L. extracts.
Savikin K, Menković N, Zdunić G, Stević T, Radanović D, Janković T.
Z Naturforsch C. 2009 May-Jun;64(5-6):339-42.
- Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS.
Aberham A, Schwaiger S, Stuppner H, Ganzera M.
J Pharm Biomed Anal. 2007 Nov 5;45(3):437-42.
- Free radical scavenging activities of yellow gentian (Gentiana lutea L.) measured by electron spin resonance.
Kusar A, Zupancic A, Sentjurc M, Baricevic D.
Hum Exp Toxicol. 2006 Oct;25(10):599-604.
- In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders.
Mahady GB, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR.
Phytother Res. 2005 Nov;19(11):988-91.
- Choleretic activity of Gentiana lutea ssp. symphyandra in rats.
Oztürk N, Herekman-Demir T, Oztürk Y, Bozan B, Başer KH.
Phytomedicine. 1998 Aug;5(4):283-8.
- Chemical profile, radical scavenging and cytotoxic activity of yellow gentian leaves (Genitaneae luteaefolium) grown in northern regions of Montenegro.
Balijagić J, Janković T, Zdunić G, Bosković J, Savikin K, Godevac D, Stanojković T, Jovancević M, Menković N.
Nat Prod Commun. 2012 Nov;7(11):1487-90.
- Effects of Gentiana lutea ssp. symphyandra on the central nervous system in mice.
Oztürk N, Başer KH, Aydin S, Oztürk Y, Caliş I.
Phytother Res. 2002 Nov;16(7):627-31.
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